XXIV CONGRESSO SIRC 2023

13.30-14.00 OPENING CEREMONY & WELCOME MESSAGES

Vincenzo Lionetti, SIRC President
Stefano Bonaccini, President of Emilia-Romagna
Marco Panieri, Mayor of Imola
Rodolfo Ortolani, CRIMOLA Foundation President
Rossi Andrea, Direttore Generale della AUSL di Imola

30TH ANNIVERSARY LECTIO
Chair: Vincenzo Lionetti, Scuola Superiore Sant’Anna, Pisa, Italy
Claudia Penna, University of Turin, Orbassano, Italy

 14.05-14.35

Barbara Casadei, University of Oxford, UK
“Fortune Sides with Those Who Dare”

14.40-16.00 COVID-19

Chairs: Paolo Ortolani, UO Cardiology, S.Maria della Scaletta Hospital, Imola,
Italy, Daniela Sorriento, University of Naples Federico II, Italy

 14.40-15.05

Maurizio Pesce, IRCCS – Centro Cardiologico Monzino, Milan, Italy
“SARS-CoV-2, Spike and coagulation. Expected and unexpected threats to cardiac health at the time of COVID-19”

15.05-15.20

Jessica Gambardella, University of Naples Federico II, Italy and Albert Einstein College of Medicine, New York City, USA
“COVID-19 Causes the Opening of the Mitochondrial Permeability Transition Pore in Human Endothelial Cells”

15.20-15.35

Domenico Tuttolomondo, University Hospital of Parma, Italy
“Coronary in ammation on chest computed tomography and COVID-19 mortality”

MEET THE EXPERT
Chair: Pasquale Pagliaro, University of Turin, Orbassano, Italy

15.40-16.15

Fabio A. Recchia, Scuola Superiore Sant’Anna and Institute of Clinical PhysiologyNational Council of Research, Pisa, Italy
“MicroRNAs Delivery to Repair the Infarcted Heart”

16.15-16.30 Coffee break

SIRC-INRC JOINT LECTURE
Chair: Annunziatina Laurino, University of Siena, Italy

16.30-16.55

Francesco Fedele, President of the National Institute of Cardiovascular Researches (INRC)
“Heart failure with preserved EF: a challenge and opportunity for Cardiovascular Research”

17.00-18.20 INTEGRITY AND ETHIC IN ANIMAL RESEARCH

Chair: Francesco Lodola, University of Milano-Bicocca, Italy
Michele Samaja, University of Milan, Italy

17.00-17.25

Giuliano Grignaschi, University of Milan, Italy
“EU Directive 63/2010: the best compromise between ethics and reserach needs”

17.25-17.50

Roberto Caminiti, Sapienza University, Rome, Italy
“Transparency in (animal) research and its costs”

17.50-18.05

Martina Rabino, Centro Cardiologico Monzino IRCCS, Milan, Italy
“Impaired Endothelial Function in Duchenne Muscular Dystrophyassociated Cardiomyopathy: Insights from hiPSC-derived Endothelial Cells”

18.05-18.20

Margherita Burattini, University of Verona, Italy
“MELAS Syndrome: Insights into Cardiac Mechanics”
SIRC-IACS JOINT LECTURE
Chair: Vincenzo Lionetti, Scuola Superiore Sant’Anna, Pisa, Italy

18.25-18.55

Grant Pierce, President of the International Academy of Cardiovascular Sciences (IACS)
“Using dietary axseed to treat cardiovascular disease in humans and animal models”

19.00-21.00 WELCOME COCKTAIL AND POSTER SESSION

Chair: Lucio Barile, Università della Svizzera Italiana, Bellinzona, Switzerland and Elena Guzzolino, Meyer Children’s Hospital, Florence, Italy

08.30-09.50 FROM NUTRACEUTICS TO RISTOCEUTICS

Chair: Carmine Rocca, University of Calabria, Arcavacata, Italy
Astrid Parenti, University of Florence, Italy

08.30-08.45

Antonella Fiordelisi, Federico II University of Naples, Italy
“L-Arginine supplementation as mitochondrial therapy in diabetic cardiomyopathy”

08.45-09.00

Maria Concetta Granieri, University of Calabria, Arcavacata, Italy
“Palmitate-induced cardiac lipotoxicity is relieved by Quercetin and its novel acetylated derivative Q2 through inhibition of oxidative stress and in ammation”

09.00-09.25

Lucia Morbidelli, University of Siena, Italy
“Vascular endothelium as target of protective activities by nutraceutical”

09.25-09.50

Vincenzo Calderone, University of Pisa, Italy
“Sulfaceuticals: emerging modulators of cardiovascular health”
STATE OF THE ART LECTURE
Chair: Francesco Moccia, University of Pavia, Italy

9.50-10.20

Gaetano Thiene, University of Padua, Italy
“Sudden death in the athletes with concealed arrhythmogenic cardiomyopathy: how to prevent?”

16.15-16.30 Coffee break

10.35-11.55 GENDER DIFFERENCES

Chair: Pietro Ameri, University of Genoa, Italy
Rosalinda Madonna, University of Pisa, Italy

10.35-11.00

Elena Osto, Medical University of Graz, Austria
“Impact of sex and gender on endothelial metabolism and function in cardiometabolic disease”

11.00-11.25

Giovanna Maria Pelà, University of Parma, Italy
“The female side of the heart: sex differences in cardiovascular diseases”

11.25-11.40

Maria Angela Guzzardi, Institute of Clinical Physiology, National Research Council, Pisa, Italy
“The transfer of gut microbiota/metabolites from children to mice affects cardiometabolic development and induces sex-dimorphism in recipients”

11.40-11.55

Claudia Maniezzi, University of Milano-Bicocca, Milan, Italy
“Electrophysiological effects of estrogen on hiPSC-derived cardiomyocytes of a patient affected by estrogen-sensitive Long-QT Syndrome Type 2”

INDUSTRY SESSION

11.55-12.10

Michele Di Palo, Foreseebiosystems srl
“In Vitro Assessment of acute and chronic cardiotoxicity on microelectrode arrays with laser cell optoporation”

SIRC TRASLATIONAL REASERCH LECTURE
Chair: Sveva Bollini, University of Genoa, Italy

12.10-12.40

Giovanni Camici, University of Zurich, Switzerland
“Cardiovascular aging: a translational perspective”

14:15-16.00 BIOTECHNOLOGY, BIOENGINEERING AND ARTIFICIAL INTELLIGENCE

Chair: Michele Masetti, UOC General Surgery, S.Maria della Scaletta Hospital, Imola, Italy
Michele Miragoli, University of Parma, Italy

14.15-14.40

Valeria Chiono, Polytechnic University of Turin, Italy
“Design of biomimetic substrates for cardiac regeneration through direct reprogramming”

14.40-15.05

Christian Vergara, Polytechnic University of Milan, Italy
“Computational analyses of cardiovascular problems: a quantitative/non-invasive method for electrophysiology, hemodynamics, cardiac perfusion”

15.05-15.20

Marco Mergiotti, University of Turin, Italy
“Interrogating Early Molecular Events of Doxorubicin-induced Cardiotoxicity at Single-cell Level to Identify New Therapeutic Approaches”

15.20-15.35

Luca Sala, University of Milano-Bicocca, Milan, Italy and Istituto Auxologico Italiano IRCCS, Milan, Italy
“Use of hiPSC-derived cardiomyocytes to study LQTS-variant specific proarrhythmic effects of drugs”

15.40-17.00 CLIMATE CHANGES AND ENVIRONMENTAL POLLUTION

Chair: Francesco Moccia, University of Pavia, Italy
Teresa Pasqua, University of Catanzaro, Italy

15.40-16.05

Franca Barbic, Humanitas University, Rozzano, Italy
“Environmental temperature and cardiac autonomic control: from experimental observations to preventive interventions and save energy”

16.05-16.30

Giovanni Li Volti, University of Catania, Italy
“The impact of cigarette smoke and reduced risk products aerosol on endothelial function: the REPLICA project”

16.30-16.45

Mirko Hu, University of Parma, Italy
“Assessing the Impact of Air Pollution on Human Embryonic Cardioids Using Innovative Longitudinal Monitoring and Machine Learning”

16.45-17.00

Mariacristina Filice, University of Calabria, Arcavacata, Italy
“The influence of environmental hypoxia on the goldfish sh (Carassius auratus) heart: from functional responses to mitochondrial molecular mechanisms”

16.15-16.30 Coffee break

INDUSTRY SESSION

17.20-17.35

Caroline O’Riordan, FUJIFILM VisualSonics, Inc
“Enhancing cardiology research: unraveling early dysfunction and molecular targets non-invasively through ultrasound and photoacustic technology”
VALSALVA PRIZE LECTURE
Introduced by the SIRC President Vincenzo Lionetti and CRIMOLA Foundation President Rodolfo Ortolani

Chair: Teresa Pasqua, University of Catanzaro, Italy

17.45-18.10

Gaetano Santulli, University of Naples Federico II, Italy and Albert Einstein College of Medicine, New York, USA
“The (uneasy) road from basic research to clinical trials: Lessons from COVID-19 and endothelial (dys)function”

18.10-19.00Meeting of the SIRC Assembly

SOCIAL DINNER

08.30-09.50 CARDIOVASCULAR MISCELLANEA

Chair: Claudia Penna, University of Turin, Orbassano, Italy
Astrid Parenti, University of Florence, Italy

08.30-08.55

Carlo Gabriele Tocchetti, University of Naples Federico II, Italy
“Cancer and Heart: dangerous liaisons”

08.55-09.20

Antonio Paolo Beltrami, University of Udine, Italy
“Protective role of BPIFB4 in ischemic heart disease”

09.20-09.35

Sophie Cnudde, University of Turin, Turin, Italy
“Phosphoinositide 3-kinase C2α (PI3KC2α) controls cardiac contractility through regulation of β2-adrenergic receptor recycling”

09.35-09.50

Niketa Sareen, University of Manitoba, Winnipeg, Canada
“Reduced cyclooxygenase 2 levels after hypoxia exposure result in the loss of immunoprivilege of allogeneic mesenchymal stem cells”
GUIDO TARONE LECTURE
Chair: Alessandra Ghigo, University of Turin, Turin, Italy

09.55-10.25

Sanjiv Dhingra, University of Manitoba, Winnipeg, Canada
“Immunomodulation of allogeneic stem cells for cardiac regenerative medicine”

10.25-10.40 Coffee Break

10.40-12.00 AGING

Chair: Massimo Menetti, UO Geriatrics, S.Maria della Scaletta Hospital, Imola, Italy – Stefano Tarantini, University of Oklahoma Health Sciences Center, USA;

10:40-11.05

Balwant S. Tuana, University of Ottawa, Canada
“The centrosome in cardiac development, disease and aging”

11.05-11.30

Zoltan Ungvari, University of Oklahoma Health Sciences Center, USA
“Endothelial senescence: mechanisms and functional consequences”

11.30-11.45

Yulia Goshovska, Università della Svizzera Italiana, Lugano, Switzerland and Cardiocentro Ticino Institute, Bellinzona, Switzerland
“Reduction of doxorubicine-induced senescence does not provide cardioprotective effect in mice”

11.45-12.00

Giulio Agnetti, University of Bologna, Italy and Johns Hopkins School of Medicine, Baltimore, USA
“Understanding the Pathobiology of Intermediate Filaments to Curb Acute and Chronic Cardiac Dysfunction”

VALSALVA PRIZE LECTURE
Introduced by the SIRC President Vincenzo Lionetti and CRIMOLA Foundation President Rodolfo Ortolani
Chair: Andrea Gerbino, University of Bari, Italy

12.05-12.30

Giuseppe Ristagno, Mario Negri Institute and University of Milan, Milan, Italy
“Cardioprotection by noble gas Argon”

12.35-13.30 CEREMONY RESEARCHER AWARDS

Chair: Vincenzo Lionetti, SIRC President
Claudia Penna, SIRC Vice-President

13.30 FINAL REMARKS & TAKE-HOME MESSAGES

Chair: Vincenzo Lionetti, SIRC President
Andrea Gerbino, SIRC Secretary

The Registration to the Meeting is mandatory to be enabled to attend the Sessions and the Conference events (Welcome Party, Lunches, Coffee Breaks, and Social Events). Paid Registration is also mandatory to have the accepted Abstract included in the published Conference Proceedings and eventually Vascular Pharmacology. To this end it is mandatory to complete the registration process by the deadline of October the 1st, 2021.
Please follow the instructions herein described:

The registration procedure is as follow:
you must proceed with the Payment by Bank Transfer (IBAN: IT79Z0306909606100000174834).
“For transfers from non-EU countries, the BIC/SWIFT code ‘BCITITMM’ must be added.”
Send your payment receipt As Soon As Possible, as it takes some time to process the payment, to segreteriasirc@sirc-cardio.it. Your payment should be received, preferably, by us on or before October 1st, 2023.

Failure to pay the required amount on this date could result in the exclusion of the Abstract(s) from the Conference Proceedings. Nevertheless, payment can be completed even at the meeting avenue by cash.

Conference Fees

SIRC 2023 conference fees cover: attendance of Conference Delegates to the Sessions of the Meeting, Welcome Reception & Conference material, all Conference Lunches, all Coffee Breaks.

I costi sono da intendersi come segue:

Before/After October 1st
Regular member registration 100/180 euro
Regular non-member registration 300/350 euro
Member PhD student 40/50 euro
Non-member PhD student 120/150 euro
One day registration
Regular member/non-member 150 euro
PhD student 60 euro

APERTURA finestra Submission sulle 8 macroaree:
1 Maggio 2023

SCADENZA Submission:
12 Settembre 2023

* A Certificate must be send together to the Bank transfer receipt at segreteriasirc@sirc-cardio.it.