XXIII CONGRESSO SIRC 2021

14.00-14.30 Opening Ceremony & Welcome Messages from the President and the Authorities

14.30-15.50 SYMPOSIUM 1:

REGENERATIVE MEDICINE: FROM PARACRINE THERAPY TO GENETIC MANIPULATION TO ACHIEVE CARDIAC REPAIR
Chairs: R. Madonna (UNIPI, Italy) – S. Bollini (UNIGE, Italy)

 14.30-14.55 Key Lecture:

Lucio Barile (Cardiocentro Ticino Foundation, Lugano, Swiss Institute for Regenerative Medicine, Switzerland)
“Translational applications of exosomes in ischemic heart disease: where are we now?”

14.55-15.20 Key Lecture:

Daniele Torella (Università della Magna Grecia, CZ, Italy) 
“Senescence-released cardiac tissue specific progenitors regain stemness and myocardial regeneration in aging.”

15.20-15.35 Selected Oral presentation

Sharon Negri (University of Pavia, Italy)
“Optical stimulation of endothelial colony forming cells plated on light-sensitive conjugated polymers induces a TRPV1-mediated increase in intracellular Ca2+ concentration”

15:35-15:50 Selected Oral Presentation

Fabiola Marino (Magna Grecia University, CZ, Italy)
“The piRNome of adult cardiac/progenitor cells: a novel procardiogenic piRNA promotes their specification and differentiation in cardiomyocytes in vitro”

  15.50-16.10 Coffee Break            


16.10-17.30 SYMPOSIUM 2:

NON-CARDIOMYOCYTE CONTRIBUTIONS TO HEART DISEASE
Chairs: A. Ghigo (UNITO, Italy) – G. Tocchetti (UNINA, Italy)

 16.10-16.35 Key Lecture:

Milena Bellin (Leiden University Medical Center, the Netherlands & UNIPD, Italy) “Engineered models of the human heart: directions and challenges”

16.35-17.00 Key Lecture:

Pietro Ameri (UNIGE, Italy)
“Cardiac fibroblasts in doxorubicin cardiotoxicity: just bystanders?”

17.00-17.15   Selected Oral Presentation

Rendon Angel Azucena (Istituto Cardiocentro Ticino_EOC, Lugano, e Università Svizzera Italiana, Switzerland)
“Doxorubicin-induced cardiotoxicity enhance SARS-CoV-2 infection susceptibility in human cardiomyocytes”

17.15-17.30   Selected Oral Presentation

Pawan Faris (University of Pavia, Italy)
“Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) induces intracellular Ca2+ signals through activation of endo-lysosomal two-pore channel (TPC) in cardiac mesenchymal Stromal Sells”

 

17.30-18.15 VALSALVA PRIZE LECTURE

introduced by the SIRC President, Prof. Tommaso Angelone

17.35-18.15 Valsalva Lecture

To be delivered by the Winner of the Valsalva Prize (hopefully supported by Fondazione Cassa di Risparmio di Imola)

  18.00-19.30 Poster review            

 

09.00-10.20 SYMPOSIUM 3:

NEW FUEL IN COMPUTATIONAL CARDIOLOGY: COVERING THE ROAD FROM PREDICTION TO TREATMENT
Chairs: M. Miragoli (UNIPR, Italy) – F. Lodola (UNIMIB, Italy)

09.00-09.25 Key Lecture:

Alfonso Bueno-Orovio (Oxford University, UK)
“Computational Modelling of Hypertrophic Cardiomyopathy”

09.25-09.50 Key Lecture:

Stefano Severi (University of Bologna, Italy)
“From lab animals to humans, from in vitro to in vivo: an update on computational models of human cardiac cells”

09.50-10.05   Selected Oral Presentation

Francesco Lo Muzio (University of Verona, Italy)
“Supervised machine learning classifiers and cardiac kinematics support decision-making during open-chest surgery of Tetralogy of Fallot patients”

10.05-10.20   Selected  Oral Presentation

Massimiliano Zaniboni (University of Parma, Italy)
“A new harmonic model of cardiac excitation-contraction coupling”

  10.20-10.35 Coffee Break           

10.35-11.05 STATE OF THE ART LECTURE:
Chair: F. Moccia (UNIPV, Italy)

Leonardo Sacconi (INO-CNR and LENS, Firenze)
“Advanced optical methods to monitor and control the cardiac electrical activity”

11.10-11.55 SYMPOSIUM 4:

THE RIGHT VENTRICLE IN ARTERIAL PULMONARY HYPERTENSION
Chairs: Rosalinda Madonna (UNIPI, Italy) – Valentina Mercurio (Federico II University, NA, Italy)

11.10-11.35 Key Lecture:

Roberto Badagliacca (UNIROMA1, Italy)
“Right ventricular adaptation to pulmonary hypertension: from pathobiology to ventricular-arterial coupling”

11.35-11.50 Selected Oral presentation

Matteo Mazzola (University of Pisa, Italy)
“Isolated exercise-induced pulmonary hypertension is associated with clinical worsening and poor immunological control in HIV patients”

11.50-12.05 Selected Oral presentation

Annunziata Laurino (University of Florence, Italy)
“Interleukin 6 rapidly modifies Hyperpolarization-activated Cyclic nucleotide–gated (HCN) channel expression in vitro and its level is linearly related to HCN isoforms in human atria”

 

12.05-12.30 GUIDO TARONE LECTURE

Chair: P. Pagliaro and Claudia Penna (UNITO, Italy)
Giulio Pompilio (Direttore Scientifico Centro Cardiologico Monzino, Milano – UNIMI, Italy)
“Cell Therapy for refractory angina: research&development path”

   12.30-12.45 Sponsor Session          

Dieter Fuchs (FUJIFILM VisualSonics, Inc.)
“Towards standardization of small animal cardio imaging”

 

   12.45-13.45 Poster view and Lunch          

14.15-16.00 SYMPOSIUM 5: 

NOVEL DETERMINANTS AND EMERGING STRATEGIES TO MITIGATE THE CARDIOVASCULAR RISK
Chairs: G. Iaccarino (UNINA, Italy) – T. Pasqua (UNICZ, Italy)

14.15-14.40 Key Lecture:

Claudio Borghi (University of Bologna, Italy)
“Uric acid as determinant of cardiovascular risk: Evidence of the URRAH study”

14.40-15.05 Key Lecture:

Claudio Napoli (University of Campania “Luigi Vanvitelli”, NA, Italy)
“Epigenetics of the cardiovascular risk”

15.05-15.30 Key Lecture:

Arrigo Cicero (University of Bologna, Italy)
“Nutraceutical in the handling of cardiovascular risk: The position of the SINUT”

15.30-15.45 Selected Oral presentation

Matteo Sorge (University of Turin, Italy)
“An intrinsic mechanism of metabolic resilience influences the cardiac response to stress”

15.45-16.00 Selected Oral presentation

Carmine Rocca (University of Calabria, CS, Italy)
“The chromogranin A1-373 fragment exerts strong cardioregulatory effects by engaging neuropilin-1 through minimal changes in the protein sequence”

 

16.00-17.20 SYMPOSIUM 6:

HEART-BRAIN AXIS: AN UNEXPECTED SYNTHESIS

Chairs: V. Lionetti (SSSUP, Italy) – F. Moccia (UNIPV, Italy)

16.00-16.25 Key Lecture:

Vincenzo Lionetti (SSSUP, Italy)
“Can the brain help protect the heart?”

16.25-16.50 Key Lecture:

Federica Del Monte (UNIVERSITY OF SOUTH CAROLINA, USA, AND UNIBO, ITALY)
“”The heart of Alzheimer’s: A mindful view of HFpEF”

 16.50-17.05 Selected Oral presentation

Giulia Furini (Scuola Superiore Sant’Anna, Pisa, Italy)
“High postoperative plasma exosomal miRNAs 1, 21 and 133a depict LV reverse remodeling in patients undergoing mitral valve repair surgery”

17.05-17.20 Selected Oral presentation

Marco Mongillo (University of Padova, Italy)
“Muscle RING finger-1 is required to prevent age-related cardiac hypertrophy and interstitial remodelling”

 

   17.20-17.35  Coffee break          

17.35-19.10 SYMPOSIUM 7:

UNMASKING NEW MOLECULAR DETERMINANTS IN FAMILIAL CARDIOMYOPATHIES
Chairs: R. Coppini (UNIFI, Italy) – A. Gerbino (UNIBA, Italy)

 17.35-18.00 Key Lecture:

Andrea Barbuti (University of Milan, Italy)
“Cardiomyocytes caveolae: dynamic membrane microdomains linking mechanical dysfunction and arrhythmias”

 18.00-18.25  Key Lecture:

Cecilia Ferrantini (University of Florence, Italy)
“Mutation-dependent and -independent mechanisms of myocardial dysfunction in hypertrophic cardiomyopathy: implications for targeted therapies”

18.25-18.40   Selected Oral Presentation

Tania Zaglia (University of Padova, Italy)
“Generation and phenotyping of a novel knock-in mouse model of

18.40-18.55  Selected Oral Presentation

 Jessica Gambardella (Federico II, Naples, Italy)
“Metabolic alterations of skeletal muscle and exercise intolerance in a mouse model of Fabry Disease”

18.55-19.10  Selected Oral Presentation

Carlotta Ronchi (IIT, Milan, Italy)
“Red light-absorbing conjugated polymer optically modulates Ca2+ dynamics in cardiomyocytes derived from human induced pluripotent stem cells

19.10-19.30 Meeting of the SIRC Assembly

   20.15   Social dinner        

 09.00-10.10 SYMPOSIUM 8:

EXPLORING NOVEL SIGNALLING PATHWAYS TO UNRAVEL AND TARGET THE RELATIONSHIP BETWEEN CANCER AND THE CARDIOVASCULAR SYSTEM
Chairs: A. Parenti (UNIFI, Italy) – A. Fiorio Pla (UNITO, Italy)

 09.00-09.25 Key Lecture:

Annarosa Arcangeli (UNIFI, Italy)
“Engineering anti-hERG antibodies for cancer treatment with high cardiac safety”

09.25-09.50 Key Lecture:

Annarita Cantelmo (University of Lille, France)
“Targeting endothelial cell plasticity in disease: role of mitochondrial calcium signaling and metabolism”

09.50-10.05 Selected Oral presentation

Michele Russo (University of Turin, Italy)
“Phosphoinositide 3-kinase gamma at the crossroad between autophagy and metabolic control in doxorubicin-induced cardiomyopathy”

10.05-10.20 Selected Oral presentation

Alessandro Fantin (University of Milan, Italy)
“KIT is required for fetal liver erythropoiesis but dispensable for angiogenesis”

 

   10.20-10.30 Sponsor Session       

Tommaso Sbrana (IVTech Srl)
“IVTech: the next generation of in-vitro models”

 

   10.30-12.30 Poster view and Coffee Break       

12.30-13.00 IN THE MEMORY OF PROF. GIANNI LOSANO, CO-FUNDER AND PAST PRESIDENT OF THE ITALIAN SOCIETY OF CARDIOVASCULAR RESEARCHES

A tale of heart, life, and science, by Prof. Pasquale Pagliaro (Unito, Italy)

 13.00-13.30 CEREMONY RESEARCHER AWARDS

 13.30 REMARKS & TAKE HOME MESSAGES

The Registration to the Meeting is mandatory to be enabled to attend the Sessions and the Conference events (Welcome Party, Lunches, Coffee Breaks, and Social Events). Paid Registration is also mandatory to have the accepted Abstract included in the published Conference Proceedings and eventually Vascular Pharmacology. To this end it is mandatory to complete the registration process by the deadline of October the 1st, 2021. Please follow the instructions herein described:

The registration procedure is as follow:

• you must proceed with the Payment by Bank Transfer (IBAN: IT79Z0306909606100000174834).
• send your payment receipt As Soon As Possible, as it takes some time to process the payment, to segreteriasirc@sirc-cardio.it.

Your payment should be received, preferably, by us on or before October 1st, 2021.

Failure to pay the required amount on this date could result in the exclusion of the Abstract(s) from the Conference Proceedings. Nevertheless, payment can be completed even at the meeting avenue by cash.

Conference Fees

SIRC 2021 conference fees cover: attendance of Conference Delegates to the Sessions of the Conference, Welcome Reception & Conference material, all Conference Lunches, all Coffee Breaks.

SIRC 2021 conference fees are as follows:

Before October 1st/After October 1st

Regular Member registration 90 €/150 €

Regular Non-Member registration 300 €/350 €

Member PhD Student (Unemployed)* 40 €/50 €

Non-Member PhD Student (Unemployed)* 120 €/150 €

One-day registration

Regular Member, Non-Member 150 €

Member PhD Student (Only, Unemployed)* 60 €

* A Certificate must be send together to the Bank transfer receipt at segreteriasirc@sirc-cardio.it.

 

INFORMAZIONI GENERALI

Sede
I lavori si terranno presso il Palazzo Sersanti, 1° piano (Piazza Giacomo Matteotti, 8 – Imola (BO)), sito a 800 mt (10 minuti a piedi) dalla Stazione Ferroviaria di Imola (Piazzale Anselmo Marabini).
Parcheggio
Piazza Giacomo Matteotti è inserita in un’area pedonale e a traffico limitato.

 

• Angelone Tommaso (Presidente)
• Pasqua Teresa
• Gerbino Andrea
• Ghigo Alessandra
• Iaccarino Guido
• Lionetti Vincenzo
• Madonna Rosalinda
• Miragoli Michele
• Moccia Francesco
• Munaron Luca
• Pagliaro Pasquale
• Parenti Astrid
• Samaja Michele
• Tocchetti Carlo G.

Società Italiana di Ricerche Cardiovascolari
Via Irnerio, 48 – 40126 Bologna – Italy

Dott.ssa Pasqua Teresa
E-mail: teresa.pasqua@unicz.it

Presidente Tommaso ANGELONE (Arcavacata – CS)
Vice Presidente Francesco MOCCIA (Pavia)
Segretario Pro Tempore Teresa PASQUA (Catanzaro)
Tesoriere Michele SAMAJA (Milano)
Past President Pasquale PAGLIARO (Torino)
Consiglieri
Astrid PARENTI (Firenze)
Alessandra GHIGO (Torino)
Luca MUNARON (Torino)
Guido IACCARINO (Napoli)
Andrea GERBINO (Bari)
Michele MIRAGOLI (Parma)